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Article

Myosin Id is required for planar cell polarity in ciliated tracheal and ependymal epithelial cells.

Cytoskeleton (Hoboken, N.J.) - 1 Oct 2015

Hegan Peter S, Ostertag Eric, Geurts Aron M, Mooseker Mark S

Abstract excerpt

In wild type (WT) tracheal epithelial cells, ciliary basal bodies are oriented such that all cilia on the cell surface beat in the same upward direction. This precise alignment of basal bodies and, as a result, the ciliary axoneme, is termed rotational planar cell polarity (PCP). Rotational PCP in the multi-ciliated epithelial cells of the trachea is perturbed in rats lacking myosin Id (Myo1d). Myo1d is localized...

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Identifiers

PMID: 26446290
DOI: 10.1002/cm.21259
PMCID: PMC4715625

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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