Article
Ciliary proteins link basal body polarization to planar cell polarity regulation.
Nature genetics - 1 Jan 2008
Jones Chonnettia, Roper Venus C, Foucher Isabelle, Qian Dong, Banizs Boglarka, Petit Christine, Yoder Bradley K, Chen Ping
Abstract excerpt
Planar cell polarity (PCP) refers to coordinated polarization of cells within the plane of a cell sheet. A conserved signaling pathway is required for the establishment of PCP in epithelial tissues and for polarized cellular rearrangements known as convergent extension. During PCP signaling, core PCP proteins are sorted asymmetrically along the polarization axis; this sorting is thought to direct coordinated...
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