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Article

Coupling between hydrodynamic forces and planar cell polarity orients mammalian motile cilia.

Nature cell biology - 1 Apr 2010

Guirao Boris, Meunier Alice, Mortaud Stéphane, Aguilar Andrea, Corsi Jean-Marc, Strehl Laetitia, Hirota Yuki, Desoeuvre Angélique, Boutin Camille, Han Young-Goo, Mirzadeh Zaman, Cremer Harold, Montcouquiol Mireille, Sawamoto Kazunobu, Spassky Nathalie

Abstract excerpt

In mammals, motile cilia cover many organs, such as fallopian tubes, respiratory tracts and brain ventricles. The development and function of these organs critically depend on efficient directional fluid flow ensured by the alignment of ciliary beating. To identify the mechanisms involved in this process, we analysed motile cilia of mouse brain ventricles, using biophysical and molecular approaches. Our results...

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Identifiers

PMID: 20305650
DOI: 10.1038/ncb2040

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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