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Article

T helper cell polarization in healthy people: implications for cardiovascular disease.

Journal of cardiovascular translational research - 1 Oct 2013

Olson Nels C, Sallam Reem, Doyle Margaret F, Tracy Russell P, Huber Sally A

Abstract excerpt

Atherosclerosis is a chronic inflammatory disease characterized by T lymphocyte infiltration into the atherosclerotic plaque. Assessments of T cell subtypes have demonstrated a predominance of CD4(+) T helper (Th) cells, implicated Th1 and Th17 immunity in both human and mouse atherogenesis, and provided some evidence suggesting protective roles of Th2 and T regulatory cells. Observations that certain inbred...

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Identifiers

PMID: 23921946
DOI: 10.1007/s12265-013-9496-6
PMCID: PMC3806306

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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