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Article

Analysis of the effects of depression associated polymorphisms on the activity of the BICC1 promoter in amygdala neurones.

The pharmacogenomics journal - 1 Aug 2016

Davidson S, Shanley L, Cowie P, Lear M, McGuffin P, Quinn J P, Barrett P, MacKenzie A

Abstract excerpt

The Bicaudal C Homolog 1 (BICC1) gene, which encodes an RNA binding protein, has been identified by genome wide association studies (GWAS) as a candidate gene associated with major depressive disorder (MDD). We explored the hypothesis that MDD associated single-nucleotide polymorphisms (SNPs) affected the ability of cis-regulatory elements within intron 3 of the BICC1 gene to modulate the activity of the BICC1...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 26440730
DOI: 10.1038/tpj.2015.62
PMCID: PMC4973013

Genes

BICC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

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