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Article

The association between the CCDC88A gene polymorphism at rs1437396 and alcohol use disorder, with or without major depression disorder.

Arhiv za higijenu rada i toksikologiju - 1 Jun 2023

Bonea Maria, Coroama Constantin-Ionut, Popp Radu Anghel, Miclutia Ioana Valentina

Abstract excerpt

Girdin is a protein involved in neuronal migration and hippocampal development. It is encoded by the coiled-coil domain-containing 88A (CCDC88A) gene, located on the short arm of chromosome 2 (2p). The CCDC88A gene is modulated by the intergenic single-nucleotide polymorphism (SNP) of the rs1437396, situated 9.5 kb downstream from its transcription stop site. As recent genome-wide research has associated the T...

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Identifiers

PMID: 37357876
DOI: 10.2478/aiht-2023-74-3690
PMCID: PMC10291494

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