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Article

Transcriptional regulation at a HTR1A polymorphism associated with mental illness.

Neuropharmacology - 1 Nov 2008

Le François Brice, Czesak Margaret, Steubl Dominik, Albert Paul R

Abstract excerpt

The serotonin-1A (5-HT1A) receptor serves as a hub to regulate the activity and actions of the serotonin system, and is expressed both as a presynaptic autoreceptor on raphe neurons, and as a major postsynaptic receptor in hippocampal, cortical, and hypothalamic regions involved in mood, emotion and stress response. As such, the level of expression of 5-HT1A receptors is implicated in the development of anxiety...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to Receptor, Serotonin, 5-HT1A

Source

Identifiers

PMID: 18639564
DOI: 10.1016/j.neuropharm.2008.06.046

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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