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Article

Possible association between the pituitary adenylate cyclase-activating polypeptide (PACAP) gene and major depressive disorder.

Neuroscience letters - 14 Jan 2010

Hashimoto Ryota, Hashimoto Hitoshi, Shintani Norihito, Ohi Kazutaka, Hori Hiroaki, Saitoh Osamu, Kosuga Asako, Tatsumi Masahiko, Iwata Nakao, Ozaki Norio, Kamijima Kunitoshi, Baba Akemichi, Takeda Masatoshi, Kunugi Hiroshi

Abstract excerpt

Pituitary adenylate cyclase-activating polypeptide (PACAP, ADCYAP1: adenylate cyclase-activating polypeptide 1) is a neuropeptide with neurotransmission modulating activity. The associations of the PACAP gene with schizophrenia and hippocampal volume have been reported. We recently reported depression-like behavior in the forced swimming test in PACAP deficient mice. Here we examined a possible association...

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Source

Identifiers

PMID: 19914336
DOI: 10.1016/j.neulet.2009.11.019

Genes

ADCYAP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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