Article
Sequence variations in CREB1 cosegregate with depressive disorders in women.
Molecular psychiatry - 1 Jun 2003
Zubenko G S, Hughes H B, Stiffler J S, Brechbiel A, Zubenko W N, Maher B S, Marazita M L
Abstract excerpt
Major depressive disorder (MDD) constitutes a major public health problem worldwide and affects women twice as frequently as men. Previous linkage studies have identified a 451 kb region of 2q33-35 that exhibited significant evidence of linkage to Mood Disorders among women (but not men) from families with recurrent, early-onset MDD (RE-MDD), a severe and strongly familial subtype of MDD. This 451 kb region...
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