Article
Increased IL18 mRNA levels in peripheral artery disease and its association with triglyceride and LDL cholesterol levels: a pilot study.
Heart and vessels - 1 Jun 2016
Deser Serkan Burc, Bayoglu Burcu, Besirli Kazım, Cengiz Mujgan, Arapi Berk, Junusbekov Yerik, Dirican Ahmet, Arslan Caner
Abstract excerpt
Peripheral artery disease (PAD) typically refers to lower limb vessel ischemia caused by atherosclerotic stenosis of lower extremity arteries. IL18 is a pleiotropic pro-inflammatory cytokine reported to function as an inflammatory biomarker in cardiovascular diseases. IL18 activity is balanced by high-affinity naturally occurring IL18-binding protein (IL18BP). This study aimed to determine whether IL18, IL18 BP...
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