Article
Promoter polymorphism of interleukin-18 in angiographically proven coronary artery disease.
Angiology - 1 Jan 2000
Liu Wenwei, Tang Qizhu, Jiang Hua, Ding Xiangwu, Liu Yongsheng, Zhu Rui, Tang Yongqian, Li Bin, Wei Min
Abstract excerpt
Interleukin 18 (IL-18) is a pro-atherogenic cytokine associated with the occurrence of various cardiac complications. The IL-18 gene has a functional -137 G/C polymorphism (rs187238) in the promoter region. Using the ligase detection reaction-polymerase chain reaction, we genotyped a cohort of patients in Chinese Han population in Xiangfan region. Case patients of coronary artery disease and control patients were...
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