Article
Genotype frequency of human neutrophil antigen-3 polymorphisms in the Yi, Han, and Tibetan populations of China.
Transfusion - 1 Mar 2016
Chen Qing, Srivastava Kshitij, Liu Zhong, Xiao Jianyu, Huang Chengyin, Sun Jun, Li Min, Flegel Willy Albert
Abstract excerpt
BACKGROUND: Human neutrophil antigen-3 (HNA-3) alloantibodies can cause fatal transfusion-related acute lung injury (TRALI). Most frequencies of SLC44A2 alleles encoding the HNA-3a/b antigens have been established in Han individuals by polymerase chain reaction with sequence-specific priming (PCR-SSP). We sequenced SLC44A2 gene fragments and determined allele frequencies in three ethnicities of China. STUDY...
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