Article
Human Neutrophil Antigen Genotype and Allele Frequencies in Iranian Blood Donors.
Journal of immunology research - 1 Jan 2022
Esmaeili Behnaz, Bayat Behnaz, Alirezaee Atefe, Delkhah Mona, Mehdizadeh Mohammad Reza, Pourpak Zahra
Abstract excerpt
OBJECTIVE: Human neutrophil antigens (HNAs) can be targeted by HNA-allo antibodies and cause a variety of clinical conditions such as transfusion-related acute lung injury (TRALI) and neonatal alloimmune neutropenia (NAIN). The current study is aimed at identifying the genotype and allele frequencies of HNAs in Iranian blood donors. METHODS: A total of 150 blood samples were obtained from healthy blood donors....
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