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Article

Quantification of Colonic Stem Cell Mutations.

Journal of visualized experiments : JoVE - 25 Sept 2015

Whetstone Ryan D, Gold Barry

Abstract excerpt

The ability to measure stem cell mutations is a powerful tool to quantify in a critical cell population if, and to what extent, a chemical can induce mutations that potentially lead to cancer. The use of an enzymatic assay to quantify stem cell mutations in the X-linked glucose-6-phosphate dehydrogenase gene has been previously reported.(1) This method requires the preparation of frozen sections and incubation of...

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Identifiers

PMID: 26436534
DOI: 10.3791/53240
PMCID: PMC4692627

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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