Article
The relationships among stem cells, crypts, and villi in the small intestine of mice as determined by mutation tagging.
Developmental dynamics : an official publication of the American Association of Anatomists - 1 Dec 1996
Cosentino L, Shaver-Walker P, Heddle J A
Abstract excerpt
The number of stem cells that maintain a crypt of the small intestine is uncertain. Although the number of stem cells per crypt had been thought to be 10-20, current estimates indicate a much smaller number, possibly 1 stem cell per crypt. We report here that in SWR and C57BL/6 X SWR F1 mice, the results of mutation tagging are inconsistent with the existence of more than one stem cell per crypt. Mutations at the...
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