Article
Impact of Allele-Level HLA Mismatch on Outcomes in Recipients of Double Umbilical Cord Blood Transplantation.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation - 1 Mar 2016
Brunstein Claudio G, Petersdorf Effie W, DeFor Todd E, Noreen Harriet, Maurer David, MacMillan Margaret L, Ustun Celalettin, Verneris Michael R, Miller Jeffrey S, Blazar Bruce R, McGlave Philip B, Weisdorf Daniel J, Wagner John E
Abstract excerpt
The impact of allele-level HLA mismatch is uncertain in recipients of double umbilical cord blood (UCB) transplantation. We report a single-center retrospective study of the clinical effect of using allele-level HLA mismatch HLA-A, -B, -C, -DRB1, and -DQB1 of the 2 UCB units. We studied 342 patients with hematologic malignancy. Donor-recipient pairs were grouped according to the number of matched HLA alleles,...
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