Article
Allele-level HLA matching for umbilical cord blood transplantation for non-malignant diseases in children: a retrospective analysis.
The Lancet. Haematology - 1 Jul 2017
Eapen Mary, Wang Tao, Veys Paul A, Boelens Jaap J, St Martin Andrew, Spellman Stephen, Bonfim Carmem Sales, Brady Colleen, Cant Andrew J, Dalle Jean-Hugues, Davies Stella M, Freeman John, Hsu Katherine C, Fleischhauer Katharina, Kenzey Chantal, Kurtzberg Joanne, Michel Gerard, Orchard Paul J, Paviglianiti Annalisa, Rocha Vanderson, Veneris Michael R, Volt Fernanda, Wynn Robert, Lee Stephanie J, Horowitz Mary M, Gluckman Eliane, Ruggeri Annalisa
Abstract excerpt
BACKGROUND: The standard for selecting unrelated umbilical cord blood units for transplantation for non-malignant diseases relies on antigen-level (lower resolution) HLA typing for HLA-A and HLA-B, and allele-level for HLA-DRB1. We aimed to study the effects of allele-level matching at a higher resolution-HLA-A, HLA-B, HLA-C, and HLA-DRB1, which is the standard used for adult unrelated volunteer donor...
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