Article
Outcomes of transplantation of unrelated donor umbilical cord blood and bone marrow in children with acute leukaemia: a comparison study.
Lancet (London, England) - 9 Jun 2007
Eapen Mary, Rubinstein Pablo, Zhang Mei-Jie, Stevens Cladd, Kurtzberg Joanne, Scaradavou Andromachi, Loberiza Fausto R, Champlin Richard E, Klein John P, Horowitz Mary M, Wagner John E
Abstract excerpt
BACKGROUND: Although umbilical cord blood is an accepted alternative to bone marrow for transplantation, allele-matched bone marrow is generally regarded as the preferred graft source. Our aim was to assess leukaemia-free survival after transplantations of these alternatives compared with present HLA-matching practices, and to assess the relative effect of cell dose and HLA match, and their potential interaction...
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