Article
Impact of allele-level HLA matching on outcomes after double cord blood transplantation in adults with malignancies.
Blood advances - 11 Jul 2023
Fatobene Giancarlo, Mariano Livia, Volt Fernanda, Moreira Frederico, Conelissen Jan, Furst Sabine, Daguindau Etienne, Sirvent Anne, Peffault de Latour Régis, Rafii Hanadi, Rivera-Franco Monica M, Kenzey Chantal, Scigliuolo Graziana Maria, Cappelli Barbara, Ruggeri Annalisa, Gluckman Eliane, Rocha Vanderson
Abstract excerpt
In single unrelated cord blood transplantation (UCBT), an increasing number of HLA allele mismatches (MM) has been associated with inferior overall survival (OS) and attributed to higher transplant-related mortality (TRM). Previous studies on the role of allele-level HLA matching after double UCBT (dUCBT) showed conflicting results. In this study, we report the impact of allele-level HLA matching on the outcomes...
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