Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Combined impact of HLA-allele matching and the CD34-positive cell dose on optimal unit selection for single-unit cord blood transplantation in adults.

Leukemia & lymphoma - 1 Nov 2021

Yabe Toshio, Satake Masahiro, Odajima Takeshi, Watanabe-Okochi Naoko, Azuma Fumihiro, Kashiwase Koichi, Matsumoto Kayoko, Orihara Takeshi, Yabe Hiromasa, Kato Shunichi, Kato Koji, Kai Shunro, Mori Tetsuo, Morishima Satoko, Takanashi Minoko, Nakajima Kazunori, Murata Makoto, Morishima Yasuo

Abstract excerpt

The combined effects of HLA-allele matching at six-loci (HLA-A, -B, -C, -DRB1, -DQB1, and -DPB1) and CD34+ cell dose on clinical outcomes were analyzed in 1,226 adult cases with single-unit unrelated cord blood transplantation. In the six-loci analysis, low HLA-allele matches did not significantly increase the overall mortality compared to higher matches, whereas in the five-loci analysis excluding HLA-DPB1, they...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Cord Blood Stem Cell Transplantation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Graft vs Host Disease

Share to Hematopoietic Stem Cell Transplantation

Share to Histocompatibility Testing

Source

Identifiers

PMID: 34128753
DOI: 10.1080/10428194.2021.1929958

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Combined impact of HLA-allele matching and the CD34-positive cell dose on optimal unit selection for single-unit cord blood transplantation in adults.PMID 34128753Read ↗

Role of CD34+ Cell Dose and Allele-Level HLA Matching in Single-Unit Cord Blood Transplantation.Semantic proximity Read ↗

HLA-DPB1 mismatch induces a graft-versus-leukemia effect without severe acute GVHD after single-unit umbilical cord blood transplantation.Semantic proximity Read ↗

Selection of Cord Blood Unit by CD34+ Cell and GM-CFU Numbers and Allele-Level HLA Matching in Single Cord Blood Transplantation.Semantic proximity Read ↗

Impact of allele-level HLA matching on outcomes after myeloablative single unit umbilical cord blood transplantation for hematologic malignancy.Semantic proximity Read ↗

Impact of HLA Allele Mismatch at HLA-A, -B, -C, and -DRB1 in Single Cord Blood Transplantation.Semantic proximity Read ↗

Impact of allele-level HLA matching on outcomes after double cord blood transplantation in adults with malignancies.Semantic proximity Read ↗

Impact on outcomes of human leukocyte antigen matching by allele-level typing in adults with acute myeloid leukemia undergoing umbilical cord blood transplantation.Semantic proximity Read ↗

Guidelines for Cord Blood Unit SelectionSemantic proximity Read ↗

[The impact of HLA haplotype and alleles mismatches of donor-recipient pairs on outcome of haploidentical hematopoietic stem cell transplantation with a third part cord blood unit].Semantic proximity Read ↗

The Impact of High-resolution HLA-A, HLA-B, HLA-C, and HLA-DRB1 on Transplant-related Outcomes in Single-unit Umbilical Cord Blood Transplantation in Pediatric Patients.Semantic proximity Read ↗

Allele-level HLA matching for umbilical cord blood transplantation for non-malignant diseases in children: a retrospective analysis.Semantic proximity Read ↗

Updated Comparison of 7/8 HLA Allele-Matched Unrelated Bone Marrow Transplantation and Single-Unit Umbilical Cord Blood Transplantation as Alternative Donors in Adults with Acute Leukemia.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.