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New Approaches With Natural Product Drugs for Overcoming Multidrug Resistance in Cancer

2 Oct 2015

Abstract excerpt

Resistance to chemotherapeutic drugs is one of the main obstacles to effective cancer treatment. Multidrug resistance (MDR) is defined as resistance to structurally and/or functionally unrelated drugs, and has been extensively investigated for the last three decades. There are two types of MDR: intrinsic and acquired. Tumor microenvironment selection pressure leads to the development of intrinsic MDR, while...

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PMID: 26429711
DOI: 10.2174/1381612821666151002113546

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