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Multidrug Resistance: Are We Still Afraid of the Big Bad Wolf

14 Jun 2025

Abstract excerpt

After the era of multidrug resistance (MDR) against cytotoxic chemotherapy, the development of resistance against newly developed molecularly targeted drugs also seems inevitable. While the mechanisms involved in resistance against these two categories of anticancer drugs are different, the principles are similar: inherent resistance (also known as primary resistance) is a result of heterogeneity in cancer cells...

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PMID: 40573290
DOI: 10.3390/ph18060895

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