Progress in the studies on the molecular mechanisms associated with multidrug resistance in cancers

Abstract excerpt

Chemotherapy is one of the important methods to treat cancer, and the emergence of multidrug resistance (MDR) is one major cause for the failure of cancer chemotherapy. Almost all anti-tumor drugs develop drug resistance over a period of time of application in cancer patients, reducing their effects on killing cancer cells. Chemoresistance can lead to a rapid recurrence of cancers and ultimately patient death....

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• Drug Transport and Resistance Mechanisms
• RNA and protein synthesis mechanisms
• RNA Research and Splicing