Article
The role of single nucleotide polymorphisms in predicting prostate cancer risk and therapeutic decision making.
BioMed research international - 1 Jan 2014
Van den Broeck Thomas, Joniau Steven, Clinckemalie Liesbeth, Helsen Christine, Prekovic Stefan, Spans Lien, Tosco Lorenzo, Van Poppel Hendrik, Claessens Frank
Abstract excerpt
Prostate cancer (PCa) is a major health care problem because of its high prevalence, health-related costs, and mortality. Epidemiological studies have suggested an important role of genetics in PCa development. Because of this, an increasing number of single nucleotide polymorphisms (SNPs) had been suggested to be implicated in the development and progression of PCa. While individual SNPs are only moderately...
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