Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Comparison of genetic variation in drug ADME-related genes in Thais with Caucasian, African and Asian HapMap populations.

Journal of human genetics - 1 Feb 2016

Jittikoon Jiraphun, Mahasirimongkol Surakameth, Charoenyingwattana Angkana, Chaikledkaew Usa, Tragulpiankit Pramote, Mangmool Supachoke, Inunchot Wimala, Somboonyosdes Chayapol, Wichukchinda Nuanjun, Sawanpanyalert Pathom, He Yijing, McLeod Howard L, Chantratita Wasun

Abstract excerpt

The objectives of this study are to investigate allele frequencies of drug absorption, distribution, metabolism and elimination (ADME)-related genes in the Thai population and to compare these genes to HapMap populations including Caucasians (CEU), Africans (YRI) and Asians (CHB/JPT). Genetic variations of drug ADME-related genes in 190 Thais were investigated using drug metabolizing enzymes and transporters...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Asian People
Share to Black People

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to HapMap Project

Share to Inactivation, Metabolic

Share to Membrane Transport Proteins

Share to Pharmacogenomic Variants

Share to Thailand

Share to White People

Source

Identifiers

PMID: 26423926
DOI: 10.1038/jhg.2015.115

Genes

COMT
NAT2
TPMT
VKORC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Comparison of genetic variation in drug ADME-related genes in Thais with Caucasian, African and Asian HapMap populations.PMID 26423926Read ↗

Pharmacogenomic landscape of the Thai population from genome sequencing of 949 individuals.Semantic proximity Read ↗

Allele frequencies of single nucleotide polymorphisms of clinically important drug-metabolizing enzymes CYP2C9, CYP2C19, and CYP3A4 in a Thai population.Semantic proximity Read ↗

Distribution of genetic polymorphisms of genes encoding drug metabolizing enzymes & drug transporters - a review with Indian perspective.Semantic proximity Read ↗

Phenotype prediction and characterization of 25 pharmacogenes in Thais from whole genome sequencing for clinical implementation.Semantic proximity Read ↗

Genetic variation in metabolizing enzyme and transporter genes: comprehensive assessment in 3 major East Asian subpopulations with comparison to Caucasians and Africans.Semantic proximity Read ↗

A comprehensive Thai pharmacogenomics database (TPGxD-1): Phenotype prediction and variants identification in 942 whole-genome sequencing data.Semantic proximity Read ↗

Thai pharmacogenomics database -2 (TPGxD-2) sequel to TPGxD-1, analyzing genetic variants in 26 non-VIPGx genes within the Thai population.Semantic proximity Read ↗

Genotypic and phenotypic landscapes of 51 pharmacogenes derived from whole-genome sequencing in a Thai population.Semantic proximity Read ↗

Clinical Impact of Genetic Variants of Drug Transporters in Different Ethnic Groups within and Across RegionsSemantic proximity Read ↗

Pharmacogenetics of common SNP affecting drug metabolizing enzymes: comparison of allele frequencies between European and Malaysian/Singaporean.Semantic proximity Read ↗

Brazilian cohort and genes encoding for drug-metabolizing enzymes and drug transporters.Semantic proximity Read ↗

Inference from the relationships between linkage disequilibrium and allele frequency distributions of 240 candidate SNPs in 109 drug-related genes in four Asian populations.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.