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Brazilian cohort and genes encoding for drug-metabolizing enzymes and drug transporters.

Pharmacogenomics - 1 Jun 2020

Kim Vera, Wal Thijs van der, Nishi Miriam Yumie, Montenegro Luciana Ribeiro, Carrilho Flair Jose, Hoshida Yujin, Ono Suzane Kioko

Abstract excerpt

Background & aim: Genetic variability in drug absorption, distribution, metabolism and excretion (ADME) genes contributes to the high heterogeneity of drug responses. The present study investigated polymorphisms of ADME genes frequencies and compared the findings with populations from other continents, available in the 1000 Genome Project (1 KGP) and the Exome Aggregation Consortium (ExAC) databases....

Topics

Adult
Aged
Brazil
Cohort Studies
Female
Humans
Male
Membrane Transport Proteins
Middle Aged
Pharmaceutical Preparations
Pharmacogenetics

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Pharmacokinetics

Polymorphism, Single Nucleotide

Source

Open in PubMed Open full text

Identifiers

PMID: 32486903
DOI: 10.2217/pgs-2020-0013
PMCID: PMC7362932

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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