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Article

The role of Smad3 in the fibrotic phenotype in human vocal fold fibroblasts.

The Laryngoscope - 1 May 2016

Branski Ryan C, Bing Renjie, Kraja Iv, Amin Milan R

Abstract excerpt

OBJECTIVES/HYPOTHESIS: To investigate the role of Smad3 as a regulator of transforming growth factor (TGF)-β1-mediated cell activities associated with fibrosis in normal human vocal fold fibroblasts. We also sought to confirm the temporal stability of Smad3 knockdown via small inhibitor ribonucleic acid (siRNA). Vocal fold fibroblasts were employed to determine the effects of Smad3 knockdown on TGF-β1-mediated...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to TGF-β signaling in diseases

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Source

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Identifiers

PMID: 26422444
DOI: 10.1002/lary.25673
PMCID: PMC4814357

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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