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Article

miR-27b inhibits fibroblast activation via targeting TGFβ signaling pathway

17 Jan 2017

Abstract excerpt

BACKGROUND: MicroRNAs are a group of small RNAs that regulate gene expression at the posttranscriptional level. They regulate almost every aspect of cellular processes. In this study, we investigated whether miR-27b regulates pulmonary fibroblast activation. RESULTS: We found that miR-27b was down-regulated in fibrotic lungs and fibroblasts from an experimental mouse model of pulmonary fibrosis. The...

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Share to Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
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PMID: 28095798
DOI: 10.1186/s12860-016-0123-7

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