Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The Long Noncoding RNA DNM3OS Is a Reservoir of FibromiRs with Major Functions in Lung Fibroblast Response to TGF-β and Pulmonary Fibrosis

9 Apr 2019

Abstract excerpt

Abstract Rationale Given the paucity of effective treatments for idiopathic pulmonary fibrosis (IPF), new insights into the deleterious mechanisms controlling lung fibroblast activation, the key cell type driving the fibrogenic process, are essential to develop new therapeutic strategies. TGF-β (transforming growth factor-β) is the main profibrotic factor, but its inhibition is associated with severe side effects...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer-related molecular mechanisms research
Share to Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to RNA modifications and cancer

Source

Identifiers

PMID: 30964696
DOI: 10.1164/rccm.201807-1237oc

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The Long Noncoding RNA DNM3OS Is a Reservoir of FibromiRs with Major Functions in Lung Fibroblast Response to TGF-β and Pulmonary FibrosisPMID 30964696Read ↗

Therapeutic potential for renal fibrosis by targeting Smad3-dependent noncoding RNAsSemantic proximity Read ↗

BMP3b is a Novel Antifibrotic Molecule Regulated by Meflin in Lung FibroblastsSemantic proximity Read ↗

Idiopathic Pulmonary Fibrosis: Pathogenesis and the Emerging Role of Long Non-Coding RNAs.Semantic proximity Read ↗

Emerging roles of noncoding RNAs in idiopathic pulmonary fibrosisSemantic proximity Read ↗

Single-Cell RNA Sequencing Provides New Insights into Therapeutic Roles of Thyroid Hormone in Idiopathic Pulmonary FibrosisSemantic proximity Read ↗

Regulation of idiopathic pulmonary fibrosis: a cross-talk between TGF-β signaling and MicroRNAsSemantic proximity Read ↗

Inhibition of lncRNA PFRL prevents pulmonary fibrosis by disrupting the miR-26a/smad2 loopSemantic proximity Read ↗

Identification of Novel Long Noncoding RNAs Associated with TGF-β/Smad3-Mediated Renal Inflammation and Fibrosis by RNA SequencingSemantic proximity Read ↗

A Simultaneous Inhibition of ID1 and ID3 Protects Against Pulmonary FibrosisSemantic proximity Read ↗

Role of MicroRNAs in TGF-β Signaling Pathway-Mediated Pulmonary FibrosisSemantic proximity Read ↗

Systems Analysis of Transcriptomic and Proteomic Profiles Identifies Novel Regulation of Fibrotic Programs by miRNAs in Pulmonary Fibrosis FibroblastsSemantic proximity Read ↗

Long Noncoding RNA FENDRR Exhibits Antifibrotic Activity in Pulmonary FibrosisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.