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Article

Effects of Transforming Growth Factor-β1 on Human Vocal Fold Fibroblasts

1 Mar 2009

Abstract excerpt

OBJECTIVES: We studied the effect of transforming growth factor (TGF)-beta on immortalized human vocal fold fibroblasts. METHODS: Normal human vocal fold fibroblasts were subjected to sequential lentiviral transduction with genes for human telomerase (hTERT) and SV40 large T antigen in order to produce an "immortalized" cell line of normal phenotype. After confirmation of vocal fold fibroblast transfection, these...

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PMID: 19374154
DOI: 10.1177/000348940911800310

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