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Article

Population pharmacokinetics and pharmacodynamics of busulfan with GSTA1 polymorphisms in patients undergoing allogeneic hematopoietic stem cell transplantation.

Pharmacogenomics - 1 Jan 2015

Choi Boyoon, Kim Myeong Gyu, Han Nayoung, Kim Therasa, Ji Eunhee, Park Seonyang, Kim In-Wha, Oh Jung Mi

Abstract excerpt

AIM: A population pharmacokinetic (PPK) analysis was conducted to describe the influence of GSTA1 polymorphisms on intravenous busulfan in adults undergoing allogeneic hematopoietic stem cell transplantation. PATIENTS & METHODS: A PPK model was developed from 36 patients by a one-compartment model with first-order elimination. RESULTS: The typical value of clearance and volume of distribution were 11.0 l/h and...

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Source

Identifiers

PMID: 26419450
DOI: 10.2217/pgs.15.98

Genes

GSTA1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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