Article
Frequency of mutational changes in the embB among the ethambutol-resistant strains of Mycobacterium tuberculosis in Iran.
Journal of infection in developing countries - 28 Apr 2016
Rezaei Faranak, Haeili Mehri, Mohajeri Parviz, Hashemi Shahraki Abdolrazagh, Imani Fooladi Abbas Ali, Zahednamazi Fatemeh, Feizabadi Mohammad Mehdi
Abstract excerpt
INTRODUCTION: Early detection of drug resistant tuberculosis is one of the main priorities of TB control program. Ethambutol (EMB) is a first-line anti-TB drug that is effective for preventing treatment failures caused by Mycobacterium tuberculosis strains that are resistant to other drugs. The aim of this study was to sequence the embB gene to characterize the mutations causing resistance to EMB and to analyze...
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