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Article

Down-regulation of B cell-related genes in peripheral blood leukocytes of Parkinson's disease patients with and without GBA mutations.

Molecular genetics and metabolism - 1 Feb 2016

Kobo Hila, Bar-Shira Anat, Dahary Dvir, Gan-Or Ziv, Mirelman Anat, Goldstein Orly, Giladi Nir, Orr-Urtreger Avi

Abstract excerpt

Parkinson's disease (PD) is a common neurodegenerative disorder, caused by aging, genetic and environmental factors. Many genes and genetic loci have been implicated in autosomal dominant and recessive PD, among them SNCA, LRRK2, GBA, Parkin, DJ1 and PINK1. Mutations in the LRRK2 and GBA genes are especially common among PD patients of Ashkenazi-Jewish (AJ) origin, accounting for over a third of the patient...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 26410072
DOI: 10.1016/j.ymgme.2015.09.005

Genes

FCRL1
PINK1
SNCA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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