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Variants in PSMB9 and FGR differentially affect Parkinson's disease risk in GBA and LRRK2 mutation carriers.

Parkinsonism & related disorders - 1 Jun 2023

Shani Shachar, Goldstein Orly, Gana-Weisz Mali, Bar-Shira Anat, Thaler Avner, Gurevich Tanya, Mirelman Anat, Giladi Nir, Alcalay Roy N, Orr-Urtreger Avi

Abstract excerpt

INTRODUCTION: Recent studies found an association between Parkinson's disease (PD) and alterations in the innate immune system. However, whether the involvement of this system in two of the known genetic forms of PD, GBA-PD and LRRK2-PD, and in patients who do not carry these mutations is different, is yet to be determined. We aimed to test if genetic variations in the innate immune genes are differentially...

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Identifiers

PMID: 37116292
DOI: 10.1016/j.parkreldis.2023.105398

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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