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Article

Bioinformatics analysis and identification of genes and molecular pathways involved in Parkinson's disease in patients with mutations in the glucocerebrosidase gene.

Neuroreport - 4 Aug 2021

Xu Dan-Dan, Li Guo-Qian, Wu Zhi-Sheng, Liu Xiao-Qiang, Yang Xiao-Xia, Wang Jie-Hua

Abstract excerpt

Glucocerebrosidase (GBA) mutations occur frequently in Parkinson's disease (PD) patients. This study aims to identify potential crucial genes and pathways associated with GBA mutations in patients with PD and to further analyze new molecular mechanisms related to the occurrence of gene mutations from the perspective of bioinformatics. Gene expression profiles of datasets GSE53424 and GSE99142 were acquired from...

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Identifiers

PMID: 34132705
DOI: 10.1097/WNR.0000000000001685
PMCID: PMC8253507

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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