Article

Leveraging blood RNA expression to understand Parkinson’s disease heterogeneity and progression

2025-12-12

Abstract excerpt

<h4>ABSTRACT</h4> Parkinson’s disease (PD) exhibits substantial clinical and molecular heterogeneity, driven in part by mutations in SNCA , GBA1 and LRRK2 genes. Understanding how these genetic subtypes differ in progression and peripheral transcriptomic profiles may inform personalized prognostic and therapeutic strategies. In this study, we aim to compare disease progression trajectories and blood-based gene...

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Literature Corpus work: 95e273a7-9edc-5344-8654-5bfd91c742ad
DOI: 10.64898/2025.12.10.25342029

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