Article

Decreased SNCA Expression in Whole-Blood RNA Analysis of Parkinson’s Disease Adjusting for Lymphocytes

2024-11-19

Abstract excerpt

Blood-based RNA transcriptomics offers a promising avenue for identifying biomarkers of Parkinson’s Disease (PD) progression and may provide mechanistic insights into the systemic biological processes underlying its pathogenesis beyond the well-defined neurodegenerative features. Previous studies have indicated an age-dependent increase in neutrophil-enriched gene expression, alongside a reduction in lymphocyte co...

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Literature Corpus work: 77bc15c2-b5af-5932-bfce-419f62bcbe54
DOI: 10.1101/2024.11.18.623684

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