Article
Evaluation of CYP17A1 and LEP Gene Polymorphisms in Breast Cancer.
Oncology research and treatment - 1 Jan 2015
Karakus Nevin, Kara Nurten, Ulusoy Ali N, Ozaslan Cihangir, Tural Sengul, Okan Ismail
Abstract excerpt
BACKGROUND: Polymorphisms of estrogen synthesis- and adiposity-related genes can contribute to the development of breast cancer. The purpose of the current study was to analyze the association between CYP17A1 T27C (rs743572) and LEP -2548G>A (rs7799039) gene polymorphisms and breast cancer. MATERIAL AND METHODS: 199 breast cancer patients and 197 healthy controls were included in the study. The CYP17A1 and LEP...
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