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Article

Epigenome-wide association study suggests that SNPs in the promoter region of RETN influence plasma resistin level via effects on DNA methylation at neighbouring sites.

Diabetologia - 1 Dec 2015

Nakatochi Masahiro, Ichihara Sahoko, Yamamoto Ken, Ohnaka Keizo, Kato Yosuke, Yokota Shigeki, Hirashiki Akihiro, Naruse Keiko, Asano Hiroyuki, Izawa Hideo, Matsubara Tatsuaki, Yokota Mitsuhiro

Abstract excerpt

AIMS/HYPOTHESIS: To investigate epigenetic regulation of the plasma concentration of resistin, we performed an epigenome-wide association study for this variable and DNA methylation (DNAm) in an elderly Japanese cohort and then assessed the relation of single nucleotide polymorphisms (SNPs) associated with the plasma resistin concentration to DNAm level at identified sites. METHODS: The association of plasma...

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Source

Identifiers

PMID: 26404063
DOI: 10.1007/s00125-015-3763-9

Genes

RETN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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Epigenome-wide association study suggests that SNPs in the promoter region of RETN influence plasma resistin level via effects on DNA methylation at neighbouring sites.PMID 26404063Read ↗

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