Article
Common quantitative trait locus downstream of RETN gene identified by genome-wide association study is associated with risk of type 2 diabetes mellitus in Han Chinese: a Mendelian randomization effect.
Diabetes/metabolism research and reviews - 1 Mar 2014
Chung Chia-Min, Lin Tsung-Hsien, Chen Jaw-Wen, Leu Hsin-Bang, Yin Wei-Hsian, Ho Hung-Yun, Sheu Sheng-Hsiung, Tsai Wei-Chuan, Chen Jyh-Hong, Lin Shing-Jong, Pan Wen-Harn
Abstract excerpt
OBJECTIVE: Plasma resistin level is a potential molecular link between obesity and diabetes. Causal role of resistin, type 2 diabetes mellitus (T2DM) and genetic variants have not been thoroughly investigated. Therefore, we conducted a genome-wide association study (GWAS) to identify quantitative trait loci associated with resistin levels and investigated whether these variants were prospectively associated with...
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