Article
The effect of an APOE polymorphism on cognitive function depends on age.
Journal of neurology - 1 Jan 2014
Shin Min-Ho, Kweon Sun-Seog, Choi Jin-Su, Lee Young-Hoon, Nam Hae-Sung, Park Kyeong-Soo, Kim Hee N, Song Hye-Rim, Kim Byeong C, Choi Seong-Min, Oh Sun-Young, Jeong Seul-Ki
Abstract excerpt
It remains controversial whether APOE E4 polymorphism is related to cognitive function in general population. We aimed to evaluate an association between the APOE E4 genotype and cognitive function, and whether this association may differ by age. Cognitive function was assessed using the Korean version of modified Mini-Mental State Examination (K-mMMSE) in 10,371 Koreans aged 45-74 years in Namwon City. According...
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