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Article

Understanding the interplay between APO E polymorphism and cognition in the Italian oldest old: results from the "Mugello study".

Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology - 1 Feb 2024

Lombardi Gemma, Pancani Silvia, Bagnoli Silvia, Vannetti Federica, Nacmias Benedetta, Sorbi Sandro, Cecchi Francesca, Macchi Claudio

Abstract excerpt

INTRODUCTION: Recent data suggest that the deleterious effect on general health and cognition of ε4 allele of Apolipoprotein E (ApoE) observed in the elderly population, may attenuate in extreme aging. This study aimed to describe the ApoE genotype distribution and its relationship with cognition in a group of nonagenarians living in the Mugello area, Italy. MATERIAL AND METHODS: Cognition was evaluated using the...

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PMID: 37710144
DOI: 10.1007/s10072-023-07073-4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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