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APOE ε4 Genotype and Cognitive Reserve Effects on the Cognitive Functioning of Healthy Elders.

Dementia and geriatric cognitive disorders - 1 Jan 2017

López María Eugenia, Turrero Agustín, Delgado María Luisa, Rodríguez-Rojo Inmaculada Concepción, Arrazola Juan, Barabash Ana, Maestú Fernando, Fernández Alberto

Abstract excerpt

AIM: To test the association between cognitive performance and APOE genotype, and to assess potential modifications of this association by sociodemographic and neuroanatomical factors in a sample of 74 healthy elders. METHODS: Firstly, we explored the isolated role of the APOE ɛ4 genotype (i.e., APOE4) in different neuropsychological tests, and then the effects of its interaction with sociodemographic (i.e., age,...

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PMID: 29414814
DOI: 10.1159/000481852

Genes

APOE

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