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Article

Epigenetic Modulation in Periodontitis: Interaction of Adiponectin and JMJD3‐IRF4 Axis in Macrophages

24 Sept 2015

Abstract excerpt

Emerging evidence suggests an important role for epigenetic mechanisms in modulating signals during macrophage polarization and inflammation. JMJD3, a JmjC family histone demethylase necessary for M2 polarization is also required for effective induction of multiple M1 genes by lipopolysaccharide (LPS). However, the effects of JMJD3 to inflammation in the context of obesity remains unknown. To address this...

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PMID: 26399931
DOI: 10.1002/jcp.25201

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