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IDO1-mediated M2 macrophage polarization alleviates the progression of ankylosing spondylitis

18 Dec 2024

Abstract excerpt

Indoleamine 2,3-dioxygenase 1 (IDO1) plays an anti-inflammatory role in autoimmune disease. However, its specific function in ankylosing spondylitis (AS) remain unclear. This study aimed to investigate the potential role of IDO1 in AS. Immunofluorescence, RT-qPCR, and western blot assays were employed to measure gene expression, while ELISA was used to quantify the release of M1 macrophage and M2 macrophage...

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PMID: 39692554
DOI: 10.1080/08916934.2024.2441134

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