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Epigenetic mechanisms of macrophage activation in type 2 diabetes

9 Sept 2016

Abstract excerpt

The alarming rise of obesity and type 2 diabetes (T2D) has put a tremendous strain on global healthcare systems. Over the past decade extensive research has focused on the role of macrophages as key mediators of inflammation in T2D. The inflammatory environment in the obese adipose tissue and pancreatic β-cell islets creates and perpetuates imbalanced inflammatory macrophage activation. Consequences of this...

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PMID: 27613200
DOI: 10.1016/j.imbio.2016.08.011

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