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Article

Variants in the CYP7B1 gene region do not affect natural resistance to HIV-1 infection.

Retrovirology - 24 Sept 2015

Sironi Manuela, Biasin Mara, Pontremoli Chiara, Cagliani Rachele, Saulle Irma, Trabattoni Daria, Vichi Francesca, Lo Caputo Sergio, Mazzotta Francesco, Aguilar-Jimenez Wbeimar, Rugeles Maria Teresa, Cedeno Samandhy, Sanchez Jorge, Brander Christian, Clerici Mario

Abstract excerpt

BACKGROUND: The genetic bases of natural resistance to HIV-1 infection remain largely unknown. Recently, two genome-wide association studies suggested a role for variants within or in the vicinity of the CYP7B1 gene in modulating HIV susceptibility. CYP7B1 is an appealing candidate for this due to its contribution to antiviral immune responses. We analyzed the frequency of two previously described CYP7B1 variants...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 26399852
DOI: 10.1186/s12977-015-0206-0
PMCID: PMC4581478

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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