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Article

IL28B polymorphism associated with spontaneous clearance of hepatitis C infection in a Southern Brazilian HIV type 1 population.

AIDS research and human retroviruses - 1 Feb 2012

Lunge Vagner Ricardo, da Rocha Daniel Bedinote, Béria Jorge Umberto, Tietzmann Daniela Cardoso, Stein Airton Tetelbom, Simon Daniel

Abstract excerpt

About one-third of people infected with human immunodeficiency virus-1 (HIV-1) are coinfected with hepatitis C virus (HCV) because of shared transmission routes. Studies report that HIV-1 complicates hepatitis C infection by increasing HCV viral load and reducing spontaneous clearance. Single nucleotide polymorphisms (SNPs) upstream of the IL28B gene have been associated with spontaneous and treatment-induced...

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Identifiers

PMID: 21790472
DOI: 10.1089/aid.2011.0096

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