Article
Spontaneous control of HIV-1 viremia in a subject with protective HLA-B plus HLA-C alleles and HLA-C associated single nucleotide polymorphisms.
Journal of translational medicine - 5 Dec 2014
Moroni Marco, Ghezzi Silvia, Baroli Paolo, Heltai Silvia, De Battista Davide, Pensieroso Simone, Cavarelli Mariangela, Dispinseri Stefania, Vanni Irene, Pastori Claudia, Zerbi Pietro, Tosoni Antonella, Vicenzi Elisa, Nebuloni Manuela, Wong Kim, Zhao Hong, McHugh Sarah, Poli Guido, Lopalco Lucia, Scarlatti Gabriella, Biassoni Roberto, Mullins James I, Malnati Mauro S, Alfano Massimo
Abstract excerpt
INTRODUCTION: Understanding the mechanisms by which some individuals are able to naturally control HIV-1 infection is an important goal of AIDS research. We here describe the case of an HIV-1(+) woman, CASE1, who has spontaneously controlled her viremia for the last 14 of her 20 years of infection. METHODS: CASE1 has been clinically monitored since 1993. Detailed immunological, virological and histological...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
