Article
Associations of human leukocyte antigen DRB with resistance or susceptibility to HIV-1 infection in the Pumwani Sex Worker Cohort.
AIDS (London, England) - 31 May 2008
Lacap Philip A, Huntington Janis D, Luo Ma, Nagelkerke Nico J D, Bielawny Thomas, Kimani Joshua, Wachihi Charles, Ngugi Elizabeth N, Plummer Francis A
Abstract excerpt
OBJECTIVE: A group of commercial sex workers in the Pumwani Sex Worker Cohort, established in 1985 in Nairobi, Kenya, remain HIV-1 uninfected despite heavy exposure to HIV-1 through active sex work. Previous studies showed that this resistance is associated with a strong CD4+ T-cell response, which suggested that human leukocyte antigen class II antigens are important in resistance/susceptibility to HIV-1...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
